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3-Deoxysappanchalcone
| Product Name | 3-Deoxysappanchalcone |
| Price: | Inquiry |
| Catalog No.: | CN05651 |
| CAS No.: | 112408-67-0 |
| Molecular Formula: | C16H14O4 |
| Molecular Weight: | 270.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Chalcones |
| Physical Desc.: | Powder |
| Source: | The heartwoods of Caesalpinia sappan Linn |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
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| Description | 3-Deoxysappanchalcone is a naturally-occurring chalcone compound isolated from Caesalpinia sappan L. (Leguminosae), which possesses anti-allergic, antiviral, anti-inflammatory and antioxidant activities. 3-Deoxysappanchalcone exerts anti-inflammatory activity via induce heme oxygenase-1 (HO-1) expression by activating the AKT/mTOR pathway in murine macrophages. 3-Deoxysappanchalcone also exhibits anti-influenza virus activity (H3N2, IC50 = 1.06 μM)[1][2]. |
| Target | IC50: 1.06 μM (H3N2)[2] |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 527.1±50.0 °C at 760 mmHg |
| Flash Point | 200.5±23.6 °C |
| Exact Mass | 270.089203 |
| LogP | 2.96 |
| Vapour Pressure | 0.0±1.4 mmHg at 25°C |