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Murrayanol
| Product Name | Murrayanol |
| Price: | Inquiry |
| Catalog No.: | CN01259 |
| CAS No.: | 144525-81-5 |
| Molecular Formula: | C24H29NO2 |
| Molecular Weight: | 363.5 g/mol |
| Purity: | >=98% |
| Type of Compound: | Alkaloids |
| Physical Desc.: | Cryst. |
| Source: | The leaves of Murraya koenigii |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Murrayanol is a natural carbazole alkaloid with a variety of biological activities. Murrayanol shows anti-inflammatory, topoisomerase I and topoisomerase II (Topoisomerase) inhibition activities. Murrayanol also as a mosquitocidal and antimicrobial[1]. |
| In Vitro | Murrayanol (Compound 2) 在抗炎试验中对人前列腺素 H 合酶同工酶 1 (hPGHS-1) 的 IC50 为 109 μg/mL，对 hPGHS-2 的 IC50 为 218 μg/mL[1]。 Murrayanol (Compound 2) 在 12.5 µg/mL 浓度下对埃及伊蚊显示 100% 的死亡率[1]。 当对酿酒酵母突变菌株进行测试时，Murrayanol (Compound 2) 在 50 µg/mL 浓度下完全抑制拓扑异构酶 I 和 II 活性[1]。 Murrayanol (Compound 2) 对克氏梭菌和大肠杆菌的 MIC1000 为 100 µg/mL，但对金黄色葡萄球菌和化脓性链球菌的 MIC100 为 25 µg/mL[1]。 |
| Density | 1.113±0.06 g/cm3(Predicted) |
| Boiling Point | 570.9±50.0 °C at 760 mmHg |
| Exact Mass | 363.22000 |
| PSA | 45.25000 |
| LogP | 6.57890 |