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Kauran-16,17-diol (ent-Kauran-16beta,17-diol)
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Product Name Kauran-16,17-diol (ent-Kauran-16beta,17-diol)
Price: Inquiry
Catalog No.: CN08200
CAS No.: 16836-31-0
Molecular Formula: C20H34O2
Molecular Weight: 306.5 g/mol
Purity: >=98%
Type of Compound: Diterpenoids
Physical Desc.: Powder
Source: The herbs of Croton laevigatus
Solvent: Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc.
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Description Kauran-16,17-diol (ent-Kauran-16β,17-diol), a natural diterpene, posseses anti-tumor and inducing-apoptosis activity, with a IC50 of 17 μM on inhibiting NO production in LPS-stimulated RAW 264.7 macrophages[1][2].
In Vitro Kauran-16,17-diol (ent-Kauran-16β,17-diol) down-regulates Bcl-2 by disruption of the Ap-2α/Rb transcription activating complex and induces E2F1 up-regulation in MCF-7 cells[1].
Density1.09g/cm3
Boiling Point422.3ºC at 760mmHg
Flash Point186.8ºC
Exact Mass306.25600
PSA40.46000
LogP4.14260
Vapour Pressure6.7E-09mmHg at 25°C
Storage condition2-8℃