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Sodium Aescinate
| Product Name | Sodium Aescinate |
| Price: | $18 / 20mg |
| Catalog No.: | CN08106 |
| CAS No.: | 20977-05-3 |
| Molecular Formula: | C54H84NaO23 |
| Molecular Weight: | 1124.2 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Aesculus hippocastanum L. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OCC1OC(OC2C(O)C(OC3OCC(C(C3O)O)O)C(OC2C(=O)O)OC2CCC3(C(C2(C)CO)CCC2(C3CC=C3C2(C)CC2C4(C3CC(C(O2)C4O)(C)C)COC(=O)C(C(OC(=O)C)C)C)C)C)C(C(C1O)O)O.[Na+] |
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| Description | Sodium aescinate is a triterpene saponin derived from Aesculus hippocastanum seeds, with anti-inflammatory and antioxidant activities[1]. Sodium aescinate inhibits hepatocellular carcinoma growth by targeting CARMA3/NF-κB pathway[2]. |
| In Vitro | Sodium aescinate can block signals transiting to downstream molecules AKT, ERK, inhibit the proliferation of breast cancer cell MCF-7 cell apoptosis and induced cell apoptosis by suppressing the activation of SRC[3]. |
| In Vivo | Sodium aescinate may effectively controls and improves wound healing in diabetic rats via its anti-inflammatory and antioxidant activities[1]. Sodium aescinate treatment can alleviate the symptom of polycystic ovary syndrome (PCOS) in rat model through regulating the PI3K/Akt/GSK3-β pathway[4]. |