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Epiyangambin
| Product Name | Epiyangambin |
| Price: | Inquiry |
| Catalog No.: | CN02743 |
| CAS No.: | 24192-64-1 |
| Molecular Formula: | C24H30O8 |
| Molecular Weight: | 446.49 g/mol |
| Purity: | >=98% |
| Type of Compound: | Lignans |
| Physical Desc.: | Powder |
| Source: | The twigs of Hernandia ovigera. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Epiyangambin is a competitive platelet activating factor receptor (PAF) antagonist that dose-dependently inhibits PAF-induced platelet aggregation. Epiyangambin also inhibits the growth of human colon cancer cells (SW480 cells)[1][2]. |
| In Vitro | Epiyangambin (0-25 µM; 24 h) 以剂量依赖性方式抑制 SW480 细胞的生长[1]。 Cell Viability Assay[1] Cell Line: SW480 cells Concentration: 0-25 µM Incubation Time: 24 h Result: Caused reductions in cell number in a dose-dependent manner. |
| In Vivo | Epiyangambin (20 mg/kg) 显著抑制血小板激活因子受体 (PAF) 诱导的大鼠血小板减少症[2]。 |
| Density | 1.183g/cm3 |
| Boiling Point | 556.1ºC at 760 mmHg |
| Flash Point | 221.1ºC |
| Exact Mass | 446.19400 |
| PSA | 73.84000 |
| LogP | 3.81340 |
| Vapour Pressure | 7.78E-12mmHg at 25°C |