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alpha-Asarone
| Product Name | alpha-Asarone |
| Price: | $23 / 20mg |
| Catalog No.: | CN06857 |
| CAS No.: | 2883-98-9 |
| Molecular Formula: | C12H16O3 |
| Molecular Weight: | 208.25 g/mol |
| Purity: | >=98% |
| Type of Compound: | Phenylpropanoids |
| Physical Desc.: | Powder |
| Source: | The seeds of Daucus carota |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | C/C=C/c1cc(OC)c(cc1OC)OC |
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| Description | Alpha-Asarone is one of the main psychoactive compounds, and possesses an antidepressant-like activity in mice.IC50 value:Target:In vitro: The results indicated that α-asarone significantly attenuated the LPS-stimulated increase in neuroinflammatory responses and suppressed pro-inflammatory cytokine production in BV-2 cells. Mechanistic study revealed that α-asarone?inhibited the LPS-stimulated activation via regulation of nuclear factor kappa-B by blocking degradation of inhibitor kappa B-alpha signaling in BV-2 microglial cells. [2]In vivo: The present results reveal that the acute treatment of α-asarone elicited biphasic responses on immobility such that the duration of the immobility time is significantly reduced at lower doses (15 and 20 mg/kg, i.p.) but increased at higher doses (50 and 100 mg/kg, i.p.) in the TST. Besides, α-asarone at higher doses (50 and 100 mg/kg, i.p.) significantly decreased the spontaneous locomotor activity.[1] |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 296.0±0.0 °C at 760 mmHg |
| Flash Point | 107.7±23.8 °C |
| Exact Mass | 208.109940 |
| PSA | 27.69000 |
| LogP | 2.98 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Storage condition | −20°C |