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Apigenin-7-glucuronide
| Product Name | Apigenin-7-glucuronide |
| Price: | $89 / 10mg |
| Catalog No.: | CN05410 |
| CAS No.: | 29741-09-1 |
| Molecular Formula: | C21H18O11 |
| Molecular Weight: | 446.36 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Yellow powder |
| Source: | The herbs of Phlomis tuberosa. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC(=O)[C@H]1O[C@@H](Oc2cc(O)c3c(c2)oc(cc3=O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O |
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| Description | Apigenin-7-glucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively. |
| Target | MMP-3:12.87 μM (IC50) MMP-8:22.39 μM (IC50) MMP-9:17.52 μM (IC50) MMP13:0.27 μM (IC50) |
| In Vitro | Apigenin-7-Oglucuronide could inhibit Matrix Metalloproteinases (MMP) activities, with IC50s of 12.87, 22.39, 17.52, 0.27 μM for MMP-3, MMP-8, MMP-9, MMP-13, respectively [1]. Scutellarin A also inhibits the migrated capacity of ACHN and 786-O cells in a dose-dependent manner. It is also revealed that after treatment with Scutellarin A (30, 60, and 90 μM) for 24 h, the apoptosis rates in ACHN and 786-O cells are remarkably enhanced dose-dependently when compared to the control groups[2]. |
| Density | 1.7±0.1 g/cm3 |
| Boiling Point | 841.8±65.0 °C at 760 mmHg |
| Flash Point | 299.0±27.8 °C |
| Exact Mass | 446.084900 |
| PSA | 187.12000 |
| LogP | -0.55 |
| Vapour Pressure | 0.0±3.3 mmHg at 25°C |
| Storage condition | ?20°C |