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Ingenol
| Product Name | Ingenol |
| Price: | Inquiry |
| Catalog No.: | CN08733 |
| CAS No.: | 30220-46-3 |
| Molecular Formula: | C20H28O5 |
| Molecular Weight: | 348.44 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | White powder |
| Source: | The seeds of Euphorbia lathyris L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | OCC1=C[C@H]2[C@H]3[C@H](C3(C)C)C[C@H]([C@]3([C@@]([C@@H]1O)(O)[C@@H](O)C(=C3)C)C2=O)C |
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| Description | Ingenol is a PKC activator, with a Ki of 30 μM, with antitumor activity. |
| Target | PKC:30 μM (Ki) |
| In Vitro | Ingenol is a PKC activator, with a Ki of 30 μM. Ingenol induces ornithine decarboxylase activity (1, 3 mM), and causes morphological changes (1 mM) in primary mouse epidermal keratinocytes. Ingenol (125 μM, 250 μM, 500 μM, 1 mM) also inhibits cell-cell communication[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 523.8±50.0 °C at 760 mmHg |
| Flash Point | 284.7±26.6 °C |
| Exact Mass | 348.193665 |
| PSA | 97.99000 |
| LogP | 2.95 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |