Home
Products
beta-Amyrenonol
| Product Name | beta-Amyrenonol |
| Price: | Inquiry |
| Catalog No.: | CN07943 |
| CAS No.: | 38242-02-3 |
| Molecular Formula: | C30H48O2 |
| Molecular Weight: | 440.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Maytenus austroyunnanensis |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
| Contact us | |
|---|---|
| First Name: | |
| Last Name: | |
| E-mail: | |
| Question: | |
| Description | β-Amyrenonol (11-Oxo-β-amyrin), an oleanolic-type triterpenoid in licorice roots, is a precursor of Glycyrrhetinic acid. β-Amyrenonol has anti-proliferative and anti-inflammatory activities, and β-Amyrenonol could function as the skeleton for the synthesis of many triterpenoids[1][2]. |
| In Vitro | β-Amyrenonol (11-Oxo-β-amyrin) inhibits cell growth of HL60 cells with an IC50 value of 26.3 µM[1]. β-Amyrenonol (11-Oxo-β-amyrin) (100 μM) significantly reduces lipopolysaccharide-induced TNFα release in THP-1 cells[1]. CYP88D6 is characterized by in vitro enzymatic activity assays and shown to catalyze the sequential two-step oxidation of β-amyrin at C-11 to produce β-Amyrenonol (11-Oxo-β-amyrin). CYP88D6 coexpressed with β-amyrin synthase in yeast also catalyzed in vivo oxidation of β-amyrin to β-Amyrenonol[3]. |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 524.0±49.0 °C at 760 mmHg |
| Flash Point | 221.3±22.4 °C |
| Exact Mass | 440.365417 |
| PSA | 37.30000 |
| LogP | 8.61 |
| Vapour Pressure | 0.0±3.1 mmHg at 25°C |