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Product Name | Taxiresinol |
Price: | Inquiry |
Catalog No.: | CN02893 |
CAS No.: | 40951-69-7 |
Molecular Formula: | C19H22O6 |
Molecular Weight: | 346.38 g/mol |
Purity: | >=98% |
Type of Compound: | Lignans |
Physical Desc.: | Powder |
Source: | The branches of Taxus wallichiana |
Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
SMILES: |
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Description | Taxiresinol is an orally active and potent lignan, that can be isolated from the heartwood of Taxus baccata. Taxiresinol shows significant antinociceptive activity[1]. |
In Vivo | Taxiresinol (100 mg/kg,口服,一次) 对对苯醌(p-benzoquinone)诱导的小鼠腹部收缩表现出显著的镇痛作用[1]。 Animal Model: Male Swiss albino mice (20-25 g)[1] Dosage: 100 mg/kg Administration: Oral administration, sixty minutes after the oral administration of test sample, the mice were intraperitoneally injected with 0.1 ml/10 g body weight of 2.5% (v/v) p-benzoquinone solution in distilled H2O. Result: Showed significant antinociceptive activity against p-benzoquinone-induced abdominal contractions (writhing movements) in mice, with a inhibitory ratio of 37.8%. |
Density | 1.3±0.1 g/cm3 |
Boiling Point | 590.3±50.0 °C at 760 mmHg |
Flash Point | 310.8±30.1 °C |
Exact Mass | 346.141632 |
PSA | 99.38000 |
LogP | 1.33 |
Vapour Pressure | 0.0±1.7 mmHg at 25°C |