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Betulonic acid
| Product Name | Betulonic acid |
| Price: | $43 / 20mg |
| Catalog No.: | CN07937 |
| CAS No.: | 4481-62-3 |
| Molecular Formula: | C30H46O3 |
| Molecular Weight: | 454.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The branches of Eucalyptus globulus Labill. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]1CC[C@H]3[C@@]([C@]1(C)CC2)(C)CC[C@@H]1[C@]3(C)CCC(=O)C1(C)C)C(=O)O |
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| Description | Betulonic acid belongs to the pentacyclic triterpenic derivative class, has antitumor activities.In vitro: BEA-NP is found over three-times more permeable than that solubilized by DMSO in Caco-2 cell monocultures.[1]In vivo: The tumor growth in the S180 berry mice orally doses with BEA-NP at 75 mg/kg is inhibited by 50%. Rubusoside is effective in solubilizing BEA, maintaining its cytotoxicity, enhancing its permeability and reducing tumor growth when orally administered.[1] antitumor activities against MGC-803, PC3, Bcap-37, A375, and MCF-7 human cancer cell lines In vivo: The animals are treated with betulonic acid amide (50 mg/kg in Tween aqueous solution) and heptral (6 mg/kg) as hepatoprotective compounds. It is found that betulonic acid amide stimulats the regenerative response in hepatocytes under conditions of combined toxic exposure and promots recovery of their qualitative and quantitative characteristics. [2] |
| Density | 1.1±0.1 g/cm3 |
| Boiling Point | 548.1±33.0 °C at 760 mmHg |
| Flash Point | 299.4±21.9 °C |
| Exact Mass | 454.344696 |
| PSA | 54.37000 |
| LogP | 8.36 |
| Vapour Pressure | 0.0±3.2 mmHg at 25°C |