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Toddalolactone
| Product Name | Toddalolactone |
| Price: | $92 / 20mg |
| Catalog No.: | CN06203 |
| CAS No.: | 483-90-9 |
| Molecular Formula: | C16H20O6 |
| Molecular Weight: | 308.33 g/mol |
| Purity: | >=98% |
| Type of Compound: | Coumarins |
| Physical Desc.: | White powder |
| Source: | The herbs of Zanthoxylum nitidum |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc2oc(=O)ccc2c(c1CC(C(O)(C)C)O)OC |
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| Description | Toddalolactone, a main component of Toddalia asiatica, inhibits the activity of recombinant human plasminogen activator inhibitor-1 (PAI-1), with an IC50 value of 37.31 μM[1]. |
| In Vitro | Toddalolactone, a natural coumarin, inhibits PAI-1 activity by preventing the formation of a stable PAI-1/uPA covalent complex, suggesting that the inhibitory effect of Toddalolactone may be due to the interference of close contact between plasminogen activator and the active center of PAI-1[1]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 530.0±50.0 °C at 760 mmHg |
| Flash Point | 195.5±23.6 °C |
| Exact Mass | 308.125977 |
| PSA | 89.13000 |
| LogP | 0.88 |
| Vapour Pressure | 0.0±1.5 mmHg at 25°C |
| Storage condition | 2-8C |