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Podophyllotoxin
| Product Name | Podophyllotoxin |
| Price: | $15 / 20mg |
| Catalog No.: | CN02990 |
| CAS No.: | 518-28-5 |
| Molecular Formula: | C22H22O8 |
| Molecular Weight: | 414.41 g/mol |
| Purity: | >=98% |
| Type of Compound: | Lignans |
| Physical Desc.: | Powder |
| Source: | The roots of Dysosma versipellis (Hance) M.Cheng ex Ying. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | COc1cc(cc(c1OC)OC)[C@H]1[C@H]2C(=O)OC[C@@H]2[C@H](c2c1cc1OCOc1c2)O |
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| Description | Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II.IC50 Value:Target: Topoisomerase II; Microtubule/TubulinPodophyllotoxin, a kind of non-alkaloid toxin lignan extracted from the roots and rhizomes of Podophyllum plant, has been shown to inhibit the growth of various carcinoma cells. Podophyllotoxin is a natural product that inhibits the polymerization of tubulin and has served as a prototype for the development of diverse antitumor agents in clinical use. |
| Density | 1.4±0.1 g/cm3 |
| Boiling Point | 597.9±50.0 °C at 760 mmHg |
| Flash Point | 210.2±23.6 °C |
| Exact Mass | 414.131470 |
| PSA | 92.68000 |
| LogP | 1.60 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |