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Prunin
| Product Name | Prunin |
| Price: | $190 / 10mg |
| Catalog No.: | CN05306 |
| CAS No.: | 529-55-5 |
| Molecular Formula: | C21H22O10 |
| Molecular Weight: | 434.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The heartwoods of Podocarpus macrophyllus. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OC[C@H]1O[C@@H](Oc2cc3O[C@H](CC(=O)c3c(c2)O)c2ccc(cc2)O)[C@@H]([C@H]([C@@H]1O)O)O |
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| Description | Prunin is a potent inhibitor of human enterovirus A71 (HEVA71). Prunin shows strong inhibitory activity against protein tyrosine phosphatase 1B (PTP1B), with an IC50 of 5.5 µM[1][2]. |
| In Vitro | Prunin exhibited dose-dependent inhibitory activity against ONOO--mediated tyrosine nitration and stimulated glucose uptake by decreasing PTP1B expression level in insulin-resistant HepG2 cells. Prunin shows significant inhibitory activity against α-glucosidase, with an IC50 of 317 ± 2.12 µM[2]. |
| Density | 1.6±0.1 g/cm3 |
| Boiling Point | 802.4±65.0 °C at 760 mmHg |
| Flash Point | 284.6±27.8 °C |
| Exact Mass | 434.121307 |
| PSA | 166.14000 |
| LogP | 0.82 |
| Vapour Pressure | 0.0±3.0 mmHg at 25°C |
| Storage condition | ?20°C |