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Friedelin
| Product Name | Friedelin |
| Price: | $242 / 5mg |
| Catalog No.: | CN07900 |
| CAS No.: | 559-74-0 |
| Molecular Formula: | C30H50O |
| Molecular Weight: | 426.7 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | Powder |
| Source: | The dry stem of Juncus effusus L. |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: | O=C1CC[C@@H]2[C@]([C@H]1C)(C)CC[C@H]1[C@@]2(C)CC[C@@]2([C@]1(C)CC[C@@]1([C@H]2CC(C)(C)CC1)C)C |
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| Description | Friedelin is isolated from isolated from the leaves of Maytenus ilicifolia(Mart). Friedelin is a noncompetitive inhibitor of CYP3A4 with IC50 and Kivalues of 10.79 μM and 6.16 μM, respectively. Friedelin is also a competitive inhibitor of CYP2E1 with IC50 and Ki values of 22.54 μM and 18.02 μM, respectively[1]. |
| Target | IC50: 10.79 μM (CYP3A4), 22.54 μM (CYP2E1); Ki: 6.16 μM(CYP3A4), 18.02 μM(CYP2E1)[1] |
| Density | 1.0±0.1 g/cm3 |
| Boiling Point | 477.2±13.0 °C at 760 mmHg |
| Flash Point | 233.9±12.1 °C |
| Exact Mass | 426.386169 |
| PSA | 17.07000 |
| LogP | 10.87 |
| Vapour Pressure | 0.0±1.2 mmHg at 25°C |
| Storage condition | 2-8℃ |