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Diosbulbin D
| Product Name | Diosbulbin D |
| Price: | Inquiry |
| Catalog No.: | CN08783 |
| CAS No.: | 66756-57-8 |
| Molecular Formula: | C19H20O6 |
| Molecular Weight: | 344.4 g/mol |
| Purity: | >=98% |
| Type of Compound: | Diterpenoids |
| Physical Desc.: | Powder |
| Source: | The roots of Dioscorea bulbifera |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
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| Description | Diosbulbin D is a potential hepatotoxic compound that can be isolated from Dioscorea bulbifera L.. Diosbulbin D induces apoptosis in L-02 cells[1]. |
| In Vitro | Diosbulbin D (10-80 μM; 12-72 h) 可诱导人正常肝脏 L-02 细胞毒性[1]。 Diosbulbin D (40 μM; 24 h) 诱导 L-02 细胞形态改变[1]。 Diosbulbin D (20-80 μM; 12-48 h) 诱导 L-02 细胞凋亡，并呈时间和浓度依赖性[1]。 Diosbulbin D (20-80 μM; 24 h) 诱导 L-02 细胞 caspase 3 的激活[1]。 Cell Viability Assay[1] Cell Line: L-02 cells Concentration: 10, 20, 40 and 80 μM Incubation Time: 12, 24, 48 and 72 h Result: Decreased L-02 cells viability in a concentration- and time-dependent manner. Apoptosis Analysis[1] Cell Line: L-02 cells Concentration: 20, 40 and 80 μM Incubation Time: 12, 24 and 48 h Result: Induced apoptosis in a time- and concentration-dependent manner. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 599.1±50.0 °C at 760 mmHg |
| Flash Point | 316.2±30.1 °C |
| Exact Mass | 344.125977 |
| PSA | 82.81000 |
| LogP | -0.35 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |