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Pseudoginsenoside F11
| Product Name | Pseudoginsenoside F11 |
| Price: | $77 / 20mg |
| Catalog No.: | CN08043 |
| CAS No.: | 69884-00-0 |
| Molecular Formula: | C42H72O14 |
| Molecular Weight: | 801.01 g/mol |
| Purity: | >=98% |
| Type of Compound: | Triterpenoids |
| Physical Desc.: | White powder |
| Source: | The roots of Panax ginseng C. A. Mey. |
| Solvent: | DMSO, Pyridine, Methanol, Ethanol, etc. |
| SMILES: | OCC1OC(OC2CC3C(C4(C2C(C)(C)C(C(C4)C)O)C)CC(C2C3(C)CCC2C2(C)CCC(O2)C(O)(C)C)O)C(C(C1O)O)OC1OC(C)C(C(C1O)O)O |
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| Description | Pseudoginsenoside-F11 (PF11), a component of Panax quinquefolium (American ginseng), has been demonstrated to antagonize the learning and memory deficits induced by scopolamine, morphine and methamphetamine in mice. IC50 value: Inhibition of diprenorphine binding with an IC50 of 6.1 μM Target:In vitro: Biochemical experiments revealed that PF11 could inhibit diprenorphine (DIP) binding with an IC50 of 6.1 μM and reduced the binding potency of morphine in Chinese hamster ovary (CHO)-μ cells [2].In vivo: One in vivo model of cisplatin-induced acute renal failure was performed. The results showed that pretreatment with Pseudoginsenoside F11 reduced cisplatin-elevated blood urea nitrogen and creatinine levels, as well as ameliorated the histophathological damage [1]. We tested the effects of Pseudoginsenoside F11 on morphine-induced development of behavioral sensitization and alterations in glutamate levels in the medial prefrontal cortex (mPFC) in freely moving mice by using in vivo microdialysis. As the results shown, Pseudoginsenoside F11 antagonized the development of behavioral sensitization and decrease of glutamate in the mPFC induced by morphine [3]. |
| Density | 1.3±0.1 g/cm3 |
| Boiling Point | 885.3±65.0 °C at 760 mmHg |
| Flash Point | 489.2±34.3 °C |
| Exact Mass | 800.492188 |
| PSA | 228.22000 |
| LogP | 5.27 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Storage condition | 2-8°C |