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Hamaudol
| Product Name | Hamaudol |
| Price: | $242 / 5mg |
| Catalog No.: | CN04477 |
| CAS No.: | 735-46-6 |
| Molecular Formula: | C15H16O5 |
| Molecular Weight: | 276.3 g/mol |
| Purity: | >=98% |
| Type of Compound: | Flavonoids |
| Physical Desc.: | Powder |
| Source: | The herbs of Ledebouriella seseloides |
| Solvent: | Chloroform, Dichloromethane, Ethyl Acetate, DMSO, Acetone, etc. |
| SMILES: |
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| Description | Hamaudol is a chromone isolated from Saposhnikovia divaricata. Hamaudol shows significant inhibitory activity on cyclooxygenase (COX)-1 and COX-2 activities with IC50 values of 0.30, 0.57 mM, respectively, and has potent analgesia and anti-inflammary effects[1][2]. |
| Target | COX-1:0.3 mM (IC50) COX-2:0.57 mM (IC50) |
| In Vivo | Hamaudol (Compound 7) increases the potency to exhibit a potent analgesia at doses of 1, 5 and 10 mg/kg in mice, although it do not show clear dose dependency[1]. |
| Boiling Point | 464.7±45.0 °C at 760 mmHg |
| Exact Mass | 276.10000 |
| PSA | 79.90000 |
| LogP | 1.88140 |
| Storage condition | 2-8°C |